NASDAQ CEO Adena Friedman runs one of the world’s largest financial services companies, including the NASDAQ stock exchange that’s home to more than 3,500 listed companies. They were also the creator of the world’s first electronic stock market.

Yet how does the company adapt to technology trends today, such as the blockchain? How does it deal with other headwinds in its business, from fewer listed companies to trends in passive vs. active investing?...

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